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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Jmv 449
Molecular formula	C38H66N8O7
IUPAC name	(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-2,6-diaminohexyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
Molecular weight	746.995
Hydrogen bond acceptor	11
Hydrogen bond donor	9
XlogP	-0.3
Synonyms	139026-66-7 H-Lysyl-psi(CH2NH)-lysyl-prolyl-tyrosyl-isoleucyl-leucine-OH AC1Q5JOW JMV449 GTPL1570 Neuromedin N (pig spinal cord), 1-de-L-lysine-2-(N2-(2,6-diaminohexyl)-L-lysine)-, (S)- AKOS024456902 MolPort-023-276-302 (2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-2,6-diaminohexyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid H-Lys-psi-(CH2NH)-lys-pro-tyr-ile-leu-OH ZINC65731292 AC1L4UQV Jmv-449 D04LEF n2-[(2s)-2,6-diaminohexyl]-l-lysyl-l-prolyl-l-tyrosyl-l-isoleucyl-l-leucine [ Show all ]
Inchi Key	TZCYVPLNMOJUIL-GULBXNHPSA-N
Inchi ID	InChI=1S/C38H66N8O7/c1-5-25(4)33(36(50)44-31(38(52)53)21-24(2)3)45-34(48)30(22-26-14-16-28(47)17-15-26)43-35(49)32-13-10-20-46(32)37(51)29(12-7-9-19-40)42-23-27(41)11-6-8-18-39/h14-17,24-25,27,29-33,42,47H,5-13,18-23,39-41H2,1-4H3,(H,43,49)(H,44,50)(H,45,48)(H,52,53)/t25-,27-,29-,30-,31-,32-,33-/m0/s1
PubChem CID	164415
ChEMBL	N/A
IUPHAR	1570
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554924	Neurotensin receptor type 1	P20789	Ntsr1	Rattus norvegicus (Rat)	424

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