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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SLIGRL-NH2
Molecular formula	C29H56N10O7
IUPAC name	(2S,3S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-N-[2-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]-3-methylpentanamide
Molecular weight	656.83
Hydrogen bond acceptor	9
Hydrogen bond donor	10
XlogP	-1.3
Synonyms	AKOS024456619 LS-191961 Ser-Leu-Ile-Gly-Arg-Leu-amide trifluoroacetate salt PAR-2 (1-6) amide (mouse, rat) trifluoroacetate salt SL-NH2 171436-38-7 H-SER-LEU-ILE-GLY-ARG-LEU-NH2 Protease-Activated Receptor-2 Activating Peptide ZINC26468553 BDBM85517 MolPort-023-276-115 Ser-Leu-Ile-Gly-Arg-Leu-NH(2) CHEMBL238078 PAR-2 (1-6) amide (mouse, rat) trifluoroacetate salt, >=97% (HPLC) SLIGRL-NH HY-P1308 Ser-Leu-Ile-Gly-Arg-Leu-amide CAS_171436-38-7 PAR-2 (1-6) amide (mouse, rat) Ser-Leu-Ile-Gly-Arg-Leu-NH2 CS-0029354 PAR-2-AP [ Show all ]
Inchi Key	SGPMJRPYYIJZPC-JYAZKYGWSA-N
Inchi ID	InChI=1S/C29H56N10O7/c1-7-17(6)23(39-27(45)21(12-16(4)5)38-25(43)18(30)14-40)28(46)35-13-22(41)36-19(9-8-10-34-29(32)33)26(44)37-20(24(31)42)11-15(2)3/h15-21,23,40H,7-14,30H2,1-6H3,(H2,31,42)(H,35,46)(H,36,41)(H,37,44)(H,38,43)(H,39,45)(H4,32,33,34)/t17-,18-,19-,20-,21-,23-/m0/s1
PubChem CID	9831050
ChEMBL	CHEMBL238078
IUPHAR	N/A
BindingDB	85517
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
313827	Proteinase-activated receptor 2	P55085	F2RL1	Homo sapiens (Human)	397
313828	Proteinase-activated receptor 2	Q63645	F2rl1	Rattus norvegicus (Rat)	397

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