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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1800285
Molecular formula	C22H20N4O3
IUPAC name	1-[(4-cyano-4-pyridin-2-ylpiperidin-1-yl)methyl]-4-oxoquinolizine-3-carboxylic acid
Molecular weight	388.427
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	-0.6
Synonyms	DA-15295 ZINC43204913 1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid FT-0723203 1144504-35-7 SCHEMBL3051312 BDBM50348232 [ Show all ]
Inchi Key	RJTJRVASUFIDQM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H20N4O3/c23-15-22(19-6-1-3-9-24-19)7-11-25(12-8-22)14-16-13-17(21(28)29)20(27)26-10-4-2-5-18(16)26/h1-6,9-10,13H,7-8,11-12,14H2,(H,28,29)
PubChem CID	25229646
ChEMBL	CHEMBL1800285
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
297930	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
297931	Muscarinic acetylcholine receptor M1	P12657	Chrm1	Mus musculus (Mouse)	460
297932	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
297933	Muscarinic acetylcholine receptor M1	P56489	CHRM1	Macaca mulatta (Rhesus macaque)	460

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