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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BAYu9773
Molecular formula	C27H36O5S
IUPAC name	4-[(4S,5R,6E,8E,10Z,13Z)-1-carboxy-4-hydroxynonadeca-6,8,10,13-tetraen-5-yl]sulfanylbenzoic acid
Molecular weight	472.64
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	6.7
Synonyms	AC1NSJU2 4-[[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]thio]benzoic acid Bay u9773, >=98% (HPLC), oil GTPL3381 1474AH 6(r)-(4-carboxyphenylthio)-5(s)-hydroxy-7(e),9(e),11(z),14(z)-eicosatetraenoic acid BDBM50033096 4-(((4S,5R,6E,8E,10Z,13Z)-1-Carboxy-4-hydroxynonadeca-6,8,10,13-tetraen-5-yl)thio)benzoic acid AKOS024457452 CHEMBL285954 4-{[(4S,5R,6E,8E,10Z,13Z)-1-carboxy-4-hydroxynonadeca-6,8,10,13-tetraen-5-yl]sulfanyl}benzoic acid BAY-u 9773 SCHEMBL1446016 154978-38-8 6(R)-(4-Carboxyphenylthio)-5(S)-hydroxy-7(E),9(E),11(Z),14(Z)eicosatetraenoic acid C27H36O5S 4-[(5S,6R,7E,9E,11Z,14Z)-1,5-dihydroxy-1-oxoicosa-7,9,11,14-tetraen-6-yl]sulfanylbenzoic acid Bay u9773 D05CNT ZINC3787144 [ Show all ]
Inchi Key	PKJINWOACFYDQN-RBVMPENBSA-N
Inchi ID	InChI=1S/C27H36O5S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(28)15-14-17-26(29)30)33-23-20-18-22(19-21-23)27(31)32/h6-7,9-13,16,18-21,24-25,28H,2-5,8,14-15,17H2,1H3,(H,29,30)(H,31,32)/b7-6-,10-9-,12-11+,16-13+/t24-,25+/m0/s1
PubChem CID	5311015
ChEMBL	CHEMBL285954
IUPHAR	3381
BindingDB	50033096
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
261944	Cysteinyl leukotriene receptor 1	Q9Y271	CYSLTR1	Homo sapiens (Human)	337
261946	Cysteinyl leukotriene receptor 1	Q2NNR5	CYSLTR1	Cavia porcellus (Guinea pig)	340
261943	Cysteinyl leukotriene receptor 2	Q9NS75	CYSLTR2	Homo sapiens (Human)	346
554576	Cysteinyl leukotriene receptor 2	Q924T9	Cysltr2	Rattus norvegicus (Rat)	309

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