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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	5-oxo-12-HETE
Molecular formula	C20H30O4
IUPAC name	(6E,8Z,10E,12S,14Z)-12-hydroxy-5-oxoicosa-6,8,10,14-tetraenoic acid
Molecular weight	334.456
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.0
Synonyms	(6E,8Z,10E,12S,14Z)-5-Oxo-12-hydroxy-6,8,10,14-icosatetraenoic acid CHEBI:137749 5-oxo-12-Hydroxy-6,8,11,13-eicosatetraenoic acid D0D2MN (6E,8Z,10E,12S,14Z)-12-hydroxy-5-oxoicosa-6,8,10,14-tetraenoic acid 8-Tarns-5-oxo-12-hete 5-oxo-12S-hydroxy-6E,8Z,10E,14Z-eicosatetraenoic acid GTPL6171 (6E,8Z,10E,12S,14Z)-12-hydroxy-5-oxoicosatetraenoic acid 8-trans-5-oxo-12-hete 5-oxo-12-Hydroxy-6,8,11,13-eicosatetraenoic CHEMBL3115778 [ Show all ]
Inchi Key	MLZJFLKEKVDNAZ-XPKTZJOPSA-N
Inchi ID	InChI=1S/C20H30O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18,21H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7-,9-6-,14-10+,15-11+/t18-/m0/s1
PubChem CID	10568747
ChEMBL	CHEMBL3115778
IUPHAR	6171
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
208778	Oxoeicosanoid receptor 1	Q8TDS5	OXER1	Homo sapiens (Human)	423

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