Zhang Lab

National University of Singapore

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	5(S)-HETE
Molecular formula	C20H32O3
IUPAC name	(5S,6E,8Z,11Z,14Z)-5-hydroxyicosa-6,8,11,14-tetraenoic acid
Molecular weight	320.473
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	5.2
Synonyms	C04805 HMS1791I05 NCGC00161235-02 (5S,6E,8Z,11Z,14Z)-5-hydroxyicosa-6,8,11,14-tetraenoic acid 5(S)-Hydroxy-6-trans-8,11,14-cis-eicosatetraenoate 5-Hydroxyeicosatetraenoate 6,8,11,14-Eicosatetraenoic acid, 5-hydroxy-, (S-(E,Z,Z,Z))- CHEMBL164813 IDI1_033913 SR-01000946914 1434AH 5(S)-hydroxyeicosatetraenoic acid 5-L-Hydroxy-6,8,11,14-eicosatetraenoic acid AC1NQXIH BML1-B01 GTPL3390 LS-63797 ZINC4546338 (+)-5(S)-Hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoic acid 5-Hydroxy-6,8,11,14-eicosatetraenoate 5S-Hydroxy-6,8,11,14-eicosatetraenoic acid CC-00077 HMS1989I05 NCGC00161235-03 (6E,8Z,11Z,14Z)-(5S)-5-Hydroxyicosa-6,8,11,14-tetraenoic acid 5(S)-Hydroxy-6-trans-8,11,14-cis-eicosatetraenoic acid 5-Hydroxyeicosatetraenoic acid 70608-72-9 D02CPV KGIJOOYOSFUGPC-JGKLHWIESA-N SR-01000946914-1 5-(S)-hydroxyeicosatetraenoic acid 5S-HETE BCBcMAP01_000020 BSPBio_001443 HMS1361I05 NCGC00161235-01 (5S,6E,8Z,11Z,14Z)-5-hydroxyeicosa-6,8,11,14-tetraenoic acid 5(S)-hydroxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid 5-Hydroxy-6,8,11,14-eicosatetraenoic acid 5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid CHEBI:28209 HMS3402I05 SCHEMBL1476909 (S)-(E,Z,Z,Z)-5-hydroxyeicosa-6,8,11,14-tetraenoic acid 5(S)-Hydroxyeicosatetraenoate 5-L-Hydroxy-6,8,11,14-eicosatetraenoate 72255-35-7 D07CJR LMFA03060002 UNII-467RNW8T91 467RNW8T91 5-Hete 5S-Hydroxy-6,8,11,14-eicosatetraenoate BDBM50027525 [ Show all ]
Inchi Key	KGIJOOYOSFUGPC-JGKLHWIESA-N
Inchi ID	InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16,19,21H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+/t19-/m1/s1
PubChem CID	5280733
ChEMBL	N/A
IUPHAR	3390
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554127	Oxoeicosanoid receptor 1	Q8TDS5	OXER1	Homo sapiens (Human)	423

zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417