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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2153468
Molecular formula	C32H22F7N3O2
IUPAC name	3,3,3-trifluoro-N-[(1S)-1-[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]ethyl]-2-hydroxy-2-[4-(1,8-naphthyridin-2-yl)phenyl]propanamide
Molecular weight	613.536
Hydrogen bond acceptor	11
Hydrogen bond donor	2
XlogP	7.2
Synonyms	BDBM50393136
Inchi Key	IRMAYPNFECPMPF-RZQQEOIVSA-N
Inchi ID	InChI=1S/C32H22F7N3O2/c1-18(19-4-6-20(7-5-19)23-10-14-26(33)25(17-23)31(34,35)36)41-29(43)30(44,32(37,38)39)24-12-8-21(9-13-24)27-15-11-22-3-2-16-40-28(22)42-27/h2-18,44H,1H3,(H,41,43)/t18-,30?/m0/s1
PubChem CID	71460333
ChEMBL	CHEMBL2153468
IUPHAR	N/A
BindingDB	50393136
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
140135	Succinate receptor 1	Q9BXA5	SUCNR1	Homo sapiens (Human)	334

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