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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL206195
Molecular formula	C28H33ClF4N4O2
IUPAC name	3-(3-chloro-4-fluorophenyl)-1-[3-(4-methylpiperazin-1-yl)propyl]-1-[(1S,2R,5S)-5-[3-(trifluoromethoxy)phenyl]-2-bicyclo[3.1.0]hexanyl]urea
Molecular weight	569.042
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	5.9
Synonyms	SCHEMBL14265834 BDBM50184922 N''-(3-chloro-4-fluorophenyl)-N-[3-(4-methyl-1-piperazinyl)-propyl]-N-[trans-5-[3-(trifluoromethoxy)phenyl]bicyclo[3.1.0]-hex-2-yl]urea
Inchi Key	IBFYJOJEMNPWGW-AVPJRLCVSA-N
Inchi ID	InChI=1S/C28H33ClF4N4O2/c1-35-12-14-36(15-13-35)10-3-11-37(26(38)34-20-6-7-24(30)23(29)17-20)25-8-9-27(18-22(25)27)19-4-2-5-21(16-19)39-28(31,32)33/h2,4-7,16-17,22,25H,3,8-15,18H2,1H3,(H,34,38)/t22-,25-,27-/m1/s1
PubChem CID	11692643
ChEMBL	CHEMBL206195
IUPHAR	N/A
BindingDB	50184922
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
129062	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
129063	Melanin-concentrating hormone receptor 1	Q8JZL2	Mchr1	Mus musculus (Mouse)	353

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