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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3290091
Molecular formula	C29H29ClN4O5
IUPAC name	(2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,4-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-2-cyclohexylacetic acid
Molecular weight	549.024
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	6.0
Synonyms	BDBM50019407 SCHEMBL17114566
Inchi Key	HFQAFXRLXRULMH-MHZLTWQESA-N
Inchi ID	InChI=1S/C29H29ClN4O5/c1-38-19-9-11-21(26(15-19)39-2)25-16-23(28(35)32-27(29(36)37)17-6-4-3-5-7-17)33-34(25)24-12-13-31-22-14-18(30)8-10-20(22)24/h8-17,27H,3-7H2,1-2H3,(H,32,35)(H,36,37)/t27-/m0/s1
PubChem CID	90644384
ChEMBL	CHEMBL3290091
IUPHAR	N/A
BindingDB	50019407
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
113661	Neurotensin receptor type 1	P20789	Ntsr1	Rattus norvegicus (Rat)	424
113660	Neurotensin receptor type 2	Q63384	Ntsr2	Rattus norvegicus (Rat)	416

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