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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2315932
Molecular formula	C25H27F3N6O2
IUPAC name	N-[1-[4-(5-hydroxypyridin-2-yl)cyclohexyl]azetidin-3-yl]-2-[[6-(trifluoromethyl)quinazolin-4-yl]amino]acetamide
Molecular weight	500.526
Hydrogen bond acceptor	10
Hydrogen bond donor	3
XlogP	3.6
Synonyms	HCMNHKKXBRMTLE-UHFFFAOYSA-N BDBM163440 US9062048, 67 N-(1-(4-(5-hydroxypyridin-2-yl)cyclohexyl)azetidin-3-yl)-2-((6-(trifluoromethyl)quinazolin-4-yl)amino)acetamide BDBM50425695 CHEMBL3704084 SCHEMBL9999128 [ Show all ]
Inchi Key	HCMNHKKXBRMTLE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H27F3N6O2/c26-25(27,28)16-3-7-22-20(9-16)24(32-14-31-22)30-11-23(36)33-17-12-34(13-17)18-4-1-15(2-5-18)21-8-6-19(35)10-29-21/h3,6-10,14-15,17-18,35H,1-2,4-5,11-13H2,(H,33,36)(H,30,31,32)
PubChem CID	54772204
ChEMBL	CHEMBL3704084
IUPHAR	N/A
BindingDB	163440
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
460213	C-C chemokine receptor-like 2	O00421	CCRL2	Homo sapiens (Human)	344

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