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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL416435
Molecular formula	C22H21NO2S
IUPAC name	(1R,10S)-15-(3-methylphenyl)-14-thia-11-azatetracyclo[8.7.0.02,7.013,17]heptadeca-2,4,6,13(17),15-pentaene-4,5-diol
Molecular weight	363.475
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	4.3
Synonyms	(5aS,11bR)-2-m-Tolyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol BDBM50057847 2-(3-Methylphenyl)-4,5,5aalpha,6,7,11bbeta-hexahydro-3-thia-5-aza-3H-cyclopenta[c]phenanthrene-9,10-diol
Inchi Key	GKLDXZHGPYSMOV-HTAPYJJXSA-N
Inchi ID	InChI=1S/C22H21NO2S/c1-12-3-2-4-14(7-12)20-10-16-21(26-20)11-23-17-6-5-13-8-18(24)19(25)9-15(13)22(16)17/h2-4,7-10,17,22-25H,5-6,11H2,1H3/t17-,22+/m0/s1
PubChem CID	10666423
ChEMBL	CHEMBL416435
IUPHAR	N/A
BindingDB	50057847
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
98777	D(1) dopamine receptor	P35406		Carassius auratus (Goldfish)	363
98778	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
98779	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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