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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL229823
Molecular formula	C28H35Cl2N5O
IUPAC name	1-[(3R,6S)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-3-(2,6-dichloropyridin-4-yl)-1-[2-[di(propan-2-yl)amino]ethyl]urea
Molecular weight	528.522
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	6.6
Synonyms	1-((3R,6S)-6-(3-cyanophenyl)bicyclo[4.1.0]heptan-3-yl)-3-(2,6-dichloropyridin-4-yl)-1-(2-(diisopropylamino)ethyl)urea BDBM50215607 SCHEMBL14266166
Inchi Key	FYELBWLBZNSANX-FKCQOYNMSA-N
Inchi ID	InChI=1S/C28H35Cl2N5O/c1-18(2)34(19(3)4)10-11-35(27(36)32-23-14-25(29)33-26(30)15-23)24-8-9-28(16-22(28)13-24)21-7-5-6-20(12-21)17-31/h5-7,12,14-15,18-19,22,24H,8-11,13,16H2,1-4H3,(H,32,33,36)/t22?,24-,28-/m1/s1
PubChem CID	44424196
ChEMBL	CHEMBL229823
IUPHAR	N/A
BindingDB	50215607
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
90154	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
90155	Melanin-concentrating hormone receptor 1	Q8JZL2	Mchr1	Mus musculus (Mouse)	353

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