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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL112134
Molecular formula	C27H22BrN5O4S
IUPAC name	N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(4-methylphenyl)pyrimidin-4-yl]naphthalene-2-sulfonamide
Molecular weight	592.468
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	5.6
Synonyms	SCHEMBL7482740 BDBM50105046 L015887 Naphthalene-2-sulfonic acid {6-[2-(5-bromo-pyrimidin-2-yloxy)-ethoxy]-5-p-tolyl-pyrimidin-4-yl}-amide
Inchi Key	FQOUOALOMZURHX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H22BrN5O4S/c1-18-6-8-20(9-7-18)24-25(33-38(34,35)23-11-10-19-4-2-3-5-21(19)14-23)31-17-32-26(24)36-12-13-37-27-29-15-22(28)16-30-27/h2-11,14-17H,12-13H2,1H3,(H,31,32,33)
PubChem CID	10897248
ChEMBL	CHEMBL112134
IUPHAR	N/A
BindingDB	50105046
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
84909	Endothelin-1 receptor	Q29010	EDNRA	Sus scrofa (Pig)	427

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