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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3663573
Molecular formula	C24H25F3N6O2
IUPAC name	[2-(2,4-dimethylpyrazol-3-yl)-6-methoxyphenyl]-[2-[[5-(trifluoromethyl)pyrazin-2-yl]amino]-7-azabicyclo[2.2.1]heptan-7-yl]methanone
Molecular weight	486.499
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	3.3
Synonyms	BDBM164162 SCHEMBL16081368 US9062078, 292
Inchi Key	FQGVMFCTXQTZLC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H25F3N6O2/c1-13-10-30-32(2)22(13)15-5-4-6-18(35-3)21(15)23(34)33-14-7-8-17(33)16(9-14)31-20-12-28-19(11-29-20)24(25,26)27/h4-6,10-12,14,16-17H,7-9H2,1-3H3,(H,29,31)
PubChem CID	90445371
ChEMBL	CHEMBL3663573
IUPHAR	N/A
BindingDB	164162
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
517744	Orexin receptor type 1	P56718	Hcrtr1	Rattus norvegicus (Rat)	416
473350	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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