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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3973097
Molecular formula	C21H17F2N5O2
IUPAC name	[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-(1H-imidazo[4,5-c]pyridin-4-yl)methanone
Molecular weight	409.397
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.3
Synonyms	BDBM50203731 SCHEMBL15896708
Inchi Key	FEAVKDCRHLEQNS-INIZCTEOSA-N
Inchi ID	InChI=1S/C21H17F2N5O2/c22-21(23)8-10-28(20(29)19-18-15(7-9-24-19)25-12-26-18)11-16(21)30-17-6-5-13-3-1-2-4-14(13)27-17/h1-7,9,12,16H,8,10-11H2,(H,25,26)/t16-/m0/s1
PubChem CID	90298275
ChEMBL	CHEMBL3973097
IUPHAR	N/A
BindingDB	50203731
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
537846	Orexin receptor type 1	P56718	Hcrtr1	Rattus norvegicus (Rat)	416
537848	Orexin receptor type 1	O43613	HCRTR1	Homo sapiens (Human)	425
537845	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444
537847	Orexin receptor type 2	P56719	Hcrtr2	Rattus norvegicus (Rat)	460

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