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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3925231
Molecular formula	C21H27N3O2
IUPAC name	(2S)-4-[2-(2,3-dihydroindol-1-yl)ethyl]-2-[(2-methylpyridin-3-yl)oxymethyl]morpholine
Molecular weight	353.466
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.8
Synonyms	US9079895, 26s BDBM186940 DYMQPSSXRFHPQS-IBGZPJMESA-N (S)-4-(2-(Indolin-1-yl)ethyl)-2-(((2-methylpyridin-3-yl)oxy)methyl)morpholine SCHEMBL14061691
Inchi Key	DYMQPSSXRFHPQS-IBGZPJMESA-N
Inchi ID	InChI=1S/C21H27N3O2/c1-17-21(7-4-9-22-17)26-16-19-15-23(13-14-25-19)11-12-24-10-8-18-5-2-3-6-20(18)24/h2-7,9,19H,8,10-16H2,1H3/t19-/m0/s1
PubChem CID	71062664
ChEMBL	CHEMBL3925231
IUPHAR	N/A
BindingDB	186940
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
537762	5-hydroxytryptamine receptor 2B	Q02152	Htr2b	Mus musculus (Mouse)	479
537763	5-hydroxytryptamine receptor 7	P32304	Htr7	Mus musculus (Mouse)	448
537760	D(3) dopamine receptor	P30728	Drd3	Mus musculus (Mouse)	446
537761	D(4) dopamine receptor	P51436	Drd4	Mus musculus (Mouse)	387

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