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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3356853
Molecular formula	C24H24ClN3O5
IUPAC name	1-[[6-chloro-4-(2,6-dimethoxyphenyl)quinazoline-2-carbonyl]amino]cyclohexane-1-carboxylic acid
Molecular weight	469.922
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.6
Synonyms	BDBM50041427
Inchi Key	DXXJCGHFVLGJMM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H24ClN3O5/c1-32-17-7-6-8-18(33-2)19(17)20-15-13-14(25)9-10-16(15)26-21(27-20)22(29)28-24(23(30)31)11-4-3-5-12-24/h6-10,13H,3-5,11-12H2,1-2H3,(H,28,29)(H,30,31)
PubChem CID	118721824
ChEMBL	CHEMBL3356853
IUPHAR	N/A
BindingDB	50041427
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
444520	Neurotensin receptor type 1	P20789	Ntsr1	Rattus norvegicus (Rat)	424
444519	Neurotensin receptor type 2	Q63384	Ntsr2	Rattus norvegicus (Rat)	416

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