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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL254065
Molecular formula	C20H29ClN6O5
IUPAC name	[(2R,3R,4R,5R)-5-[2-chloro-6-(cyclopentylamino)purin-9-yl]-3,4-dihydroxy-4-methyloxolan-2-yl]methyl N-propylcarbamate
Molecular weight	468.939
Hydrogen bond acceptor	9
Hydrogen bond donor	4
XlogP	1.9
Synonyms	BDBM50224765 2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-N-propylcarbamoyl-beta-D-ribofuranosyl)adenine
Inchi Key	DQBMXDWVUYSFGY-DPBUJNAFSA-N
Inchi ID	InChI=1S/C20H29ClN6O5/c1-3-8-22-19(29)31-9-12-14(28)20(2,30)17(32-12)27-10-23-13-15(24-11-6-4-5-7-11)25-18(21)26-16(13)27/h10-12,14,17,28,30H,3-9H2,1-2H3,(H,22,29)(H,24,25,26)/t12-,14-,17-,20-/m1/s1
PubChem CID	44447522
ChEMBL	CHEMBL254065
IUPHAR	N/A
BindingDB	50224765
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
66122	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
559349	Adenosine receptor A1	P47745	ADORA1	Cavia porcellus (Guinea pig)	326

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