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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3659221
Molecular formula	C20H21N7O2
IUPAC name	[6-methyl-3-(triazol-2-yl)pyridin-2-yl]-[2-(pyridazin-3-yloxymethyl)-7-azabicyclo[2.2.1]heptan-7-yl]methanone
Molecular weight	391.435
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	2.0
Synonyms	DMHRIBXCAZSILN-UHFFFAOYSA-N (+/-)-(6-methyl-3-(2H-1,2,3-triazol-2-yl)pyridin-2-yl)(2-((pyridazin-3-yloxy)methyl)-7-azabicyclo[2.2.1]heptan-7-yl)methanone SCHEMBL16042288 US9062078, 53 BDBM163922
Inchi Key	DMHRIBXCAZSILN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H21N7O2/c1-13-4-6-17(27-22-9-10-23-27)19(24-13)20(28)26-15-5-7-16(26)14(11-15)12-29-18-3-2-8-21-25-18/h2-4,6,8-10,14-16H,5,7,11-12H2,1H3
PubChem CID	90413513
ChEMBL	CHEMBL3659221
IUPHAR	N/A
BindingDB	163922
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
517644	Orexin receptor type 1	P56718	Hcrtr1	Rattus norvegicus (Rat)	416
470750	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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