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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3691806
Molecular formula	C20H17F3N6O2
IUPAC name	[2-(triazol-2-yl)phenyl]-[6-[5-(trifluoromethyl)pyrazin-2-yl]oxy-2-azabicyclo[2.2.1]heptan-2-yl]methanone
Molecular weight	430.391
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	2.8
Synonyms	US8969352, 1 BDBM143742 SCHEMBL16045063
Inchi Key	CWZJPIYFFDDMCP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H17F3N6O2/c21-20(22,23)17-9-25-18(10-24-17)31-16-8-12-7-15(16)28(11-12)19(30)13-3-1-2-4-14(13)29-26-5-6-27-29/h1-6,9-10,12,15-16H,7-8,11H2
PubChem CID	86271691
ChEMBL	CHEMBL3691806
IUPHAR	N/A
BindingDB	143742
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
469385	Orexin receptor type 1	P56718	Hcrtr1	Rattus norvegicus (Rat)	416
517589	Orexin receptor type 1	O43613	HCRTR1	Homo sapiens (Human)	425
469384	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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