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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3691834
Molecular formula	C23H21F3N4O3
IUPAC name	[2-methoxy-6-(1H-pyrazol-5-yl)phenyl]-[6-[5-(trifluoromethyl)pyridin-2-yl]oxy-2-azabicyclo[2.2.1]heptan-2-yl]methanone
Molecular weight	458.441
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.8
Synonyms	US8969352, 39 BDBM143778 SCHEMBL16092010
Inchi Key	CTMWEIJXXSCTJH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H21F3N4O3/c1-32-18-4-2-3-15(16-7-8-28-29-16)21(18)22(31)30-12-13-9-17(30)19(10-13)33-20-6-5-14(11-27-20)23(24,25)26/h2-8,11,13,17,19H,9-10,12H2,1H3,(H,28,29)
PubChem CID	86270575
ChEMBL	CHEMBL3691834
IUPHAR	N/A
BindingDB	143778
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
469101	Orexin receptor type 1	P56718	Hcrtr1	Rattus norvegicus (Rat)	416
517574	Orexin receptor type 1	O43613	HCRTR1	Homo sapiens (Human)	425
469100	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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