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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3264231
Molecular formula	C24H25F3N2O5
IUPAC name	(E)-3-[4-(2-hydroxyethoxy)-3,5-dimethoxyphenyl]-N-[2-[2-(trifluoromethyl)indol-1-yl]ethyl]prop-2-enamide
Molecular weight	478.468
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	3.5
Synonyms	SCHEMBL18509245
Inchi Key	CSDOJXMHPWNFON-BQYQJAHWSA-N
Inchi ID	InChI=1S/C24H25F3N2O5/c1-32-19-13-16(14-20(33-2)23(19)34-12-11-30)7-8-22(31)28-9-10-29-18-6-4-3-5-17(18)15-21(29)24(25,26)27/h3-8,13-15,30H,9-12H2,1-2H3,(H,28,31)/b8-7+
PubChem CID	90677068
ChEMBL	CHEMBL3264231
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
49361	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
49360	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
49363	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
49362	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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