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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL323243
Molecular formula	C27H28ClN5O4S
IUPAC name	4-tert-butyl-N-[6-[2-(5-chloropyrimidin-2-yl)oxyethoxy]-5-(4-methylphenyl)pyrimidin-4-yl]benzenesulfonamide
Molecular weight	554.062
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	5.9
Synonyms	SCHEMBL8801251 L013095 N-[5-(4-Methylphenyl)-6-[2-(5-chloro-2-pyrimidinyloxy)ethoxy]-4-pyrimidinyl]-4-tert-butylbenzenesulfonamide
Inchi Key	CFTVGMXKRNMJSN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H28ClN5O4S/c1-18-5-7-19(8-6-18)23-24(33-38(34,35)22-11-9-20(10-12-22)27(2,3)4)31-17-32-25(23)36-13-14-37-26-29-15-21(28)16-30-26/h5-12,15-17H,13-14H2,1-4H3,(H,31,32,33)
PubChem CID	11766844
ChEMBL	CHEMBL323243
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
40976	Endothelin-1 receptor	Q29010	EDNRA	Sus scrofa (Pig)	427

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