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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS-0435440.0001
Molecular formula	C22H19Cl2FN6
IUPAC name	1-[(2,4-dichlorophenyl)methyl]-4-[4-(4-fluorophenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidine
Molecular weight	457.334
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	5.2
Synonyms	537016-20-9 MCULE-2045221494 STL488902 AKOS001064890 MLS002699454 1-(2,4-dichlorobenzyl)-4-[4-(4-fluorophenyl)piperazino]pyrazolo[3,4-d]pyrimidine 1-[(2,4-dichlorophenyl)methyl]-4-[4-(4-fluorophenyl)piperazinyl]pyrazolo[5,4-d ]pyrimidine CHEMBL1707504 SMR001563344 Z56936128 BDBM64831 MolPort-004-414-942 1-[(2,4-dichlorophenyl)methyl]-4-[4-(4-fluorophenyl)-1-piperazinyl]pyrazolo[3,4-d]pyrimidine 1-{1-[(2,4-dichlorophenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-4-(4-fluorophenyl)piperazine cid_2474060 ST50426567 AC1M7TET MLS-0435440.0002 ZINC3356776 1-(2,4-dichlorobenzyl)-4-[4-(4-fluorophenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine 1-[(2,4-dichlorophenyl)methyl]-4-[4-(4-fluorophenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidine Oprea1_069193 [ Show all ]
Inchi Key	CFKITRQJOAIREA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H19Cl2FN6/c23-16-2-1-15(20(24)11-16)13-31-22-19(12-28-31)21(26-14-27-22)30-9-7-29(8-10-30)18-5-3-17(25)4-6-18/h1-6,11-12,14H,7-10,13H2
PubChem CID	2474060
ChEMBL	CHEMBL1707504
IUPHAR	N/A
BindingDB	64831
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
40710	G-protein coupled receptor 55	Q9Y2T6	GPR55	Homo sapiens (Human)	319

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