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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3663554
Molecular formula	C23H19BrFN7O
IUPAC name	[2-[(3-bromoimidazo[1,2-a]pyrazin-8-yl)amino]-7-azabicyclo[2.2.1]heptan-7-yl]-(3-fluoro-2-pyrimidin-2-ylphenyl)methanone
Molecular weight	508.355
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.1
Synonyms	BDBM255252 SCHEMBL16081384 US9062078, 270 BDBM164140 US9475819, 270
Inchi Key	BNPVELSULLCXLP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H19BrFN7O/c24-18-12-29-22-21(28-9-10-31(18)22)30-16-11-13-5-6-17(16)32(13)23(33)14-3-1-4-15(25)19(14)20-26-7-2-8-27-20/h1-4,7-10,12-13,16-17H,5-6,11H2,(H,28,30)
PubChem CID	90445387
ChEMBL	CHEMBL3663554
IUPHAR	N/A
BindingDB	164140
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
517464	Orexin receptor type 1	P56718	Hcrtr1	Rattus norvegicus (Rat)	416
466383	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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