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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	EP4 antagonist, BTG
Molecular formula	C26H28N2O6S
IUPAC name	4-[[4-(5-methoxypyridin-2-yl)phenoxy]methyl]-5-methyl-N-(2-methylphenyl)sulfonyloxolane-2-carboxamide
Molecular weight	496.578
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.0
Synonyms	EP4 receptor antagonists (migraine), Asterand BGC20-1531 Migraine therapy, Pharmagene 4-[4-(5-methoxypyridin-2-yl)phenoxymethyl]-5-methyl-N-[(2-methylbenzene)sulfonyl]oxolane-2-carboxamide GTPL3380 BGC201531 R-4 (migraine), Pharmagene EP4 antagonist, Pharmagene 74480-23-2 Migraine therapy, BTG D0HJ5H [ Show all ]
Inchi Key	BGXAOTTWXYPIQN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H28N2O6S/c1-17-6-4-5-7-25(17)35(30,31)28-26(29)24-14-20(18(2)34-24)16-33-21-10-8-19(9-11-21)23-13-12-22(32-3)15-27-23/h4-13,15,18,20,24H,14,16H2,1-3H3,(H,28,29)
PubChem CID	73755047
ChEMBL	N/A
IUPHAR	3380
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553365	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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