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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL215240
Molecular formula	C18H15FN4OS
IUPAC name	13-(dimethylamino)-5-(3-fluoro-4-methylphenyl)-8-thia-3,5,11-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,10,12-pentaen-6-one
Molecular weight	354.403
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.3
Synonyms	SCHEMBL6101175 9-dimethylamino-3-(3-fluoro-4-methyl-phenyl)-3H-pyrido[4'',3'':4,5]thieno[3,2-d]pyrimidin-4-one BDBM50190236
Inchi Key	BFSQSXYELOIUJW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H15FN4OS/c1-10-4-5-11(6-12(10)19)23-9-21-16-15-13(22(2)3)7-20-8-14(15)25-17(16)18(23)24/h4-9H,1-3H3
PubChem CID	11688952
ChEMBL	CHEMBL215240
IUPHAR	N/A
BindingDB	50190236
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
22609	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
22608	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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