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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3953493
Molecular formula	C25H25F3N2O3
IUPAC name	4-[1-[[3-[[4-(trifluoromethyl)phenyl]methyl]-3-azabicyclo[4.1.0]heptane-4-carbonyl]amino]cyclopropyl]benzoic acid
Molecular weight	458.481
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	1.9
Synonyms	US9181279, E23 BDBM191557 BEUQPJMSVYNQEM-UHFFFAOYSA-N SCHEMBL14486373 4-(1-(3-(4-(trifluoromethyl)benzyl)-3-azabicyclo[4.1.0]heptane-4-carboxamido)cyclopropyl)benzoic acid
Inchi Key	BEUQPJMSVYNQEM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H25F3N2O3/c26-25(27,28)20-5-1-15(2-6-20)13-30-14-18-11-17(18)12-21(30)22(31)29-24(9-10-24)19-7-3-16(4-8-19)23(32)33/h1-8,17-18,21H,9-14H2,(H,29,31)(H,32,33)
PubChem CID	71186249
ChEMBL	CHEMBL3953493
IUPHAR	N/A
BindingDB	191557
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
536535	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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