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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL442171
Molecular formula	C18H23F3N4O
IUPAC name	5-[2-(1H-imidazol-5-yl)ethylamino]-N-[4-(trifluoromethyl)phenyl]hexanamide
Molecular weight	368.404
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	2.8
Synonyms	5-[2-(1H-Imidazol-4-yl)ethylamino]-N-[4-(trifluoromethyl)phenyl]hexanamide
Inchi Key	BCZAHYKUHLEQBO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H23F3N4O/c1-13(23-10-9-16-11-22-12-24-16)3-2-4-17(26)25-15-7-5-14(6-8-15)18(19,20)21/h5-8,11-13,23H,2-4,9-10H2,1H3,(H,22,24)(H,25,26)
PubChem CID	13974543
ChEMBL	CHEMBL442171
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
442486	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
442485	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359
442487	Histamine H2 receptor	P97292	Hrh2	Mus musculus (Mouse)	397

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