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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL499301
Molecular formula	C21H23N5O
IUPAC name	N-[N'-[2-(1H-imidazol-5-yl)ethyl]carbamimidoyl]-3,3-diphenylpropanamide
Molecular weight	361.449
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	2.9
Synonyms	BDBM50413181 D0Y9IB UR-PG153 GTPL1201 N-[N'-[2-(1H-imidazol-5-yl)ethyl]carbamimidoyl]-3,3-diphenylpropanamide
Inchi Key	BCIVIRNJAROBHW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H23N5O/c22-21(24-12-11-18-14-23-15-25-18)26-20(27)13-19(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-10,14-15,19H,11-13H2,(H,23,25)(H3,22,24,26,27)
PubChem CID	25150700
ChEMBL	CHEMBL499301
IUPHAR	1201
BindingDB	50413181
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20248	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
20249	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
20247	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359

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