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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL413563
Molecular formula	C24H35NO5
IUPAC name	7-[(2R)-2-[(E,3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]but-1-enyl]-6-oxopiperidin-1-yl]heptanoic acid
Molecular weight	417.546
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.6
Synonyms	BDBM50166472 SCHEMBL4934128 7-{(R)-2-[(E)-(S)-3-Hydroxy-4-(3-methoxymethyl-phenyl)-but-1-enyl]-6-oxo-piperidin-1-yl}-heptanoic acid
Inchi Key	BCCRAFCMMIFCKU-WRBWEIJPSA-N
Inchi ID	InChI=1S/C24H35NO5/c1-30-18-20-9-6-8-19(16-20)17-22(26)14-13-21-10-7-11-23(27)25(21)15-5-3-2-4-12-24(28)29/h6,8-9,13-14,16,21-22,26H,2-5,7,10-12,15,17-18H2,1H3,(H,28,29)/b14-13+/t21-,22-/m1/s1
PubChem CID	11742697
ChEMBL	CHEMBL413563
IUPHAR	N/A
BindingDB	50166472
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20057	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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