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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL362325
Molecular formula	C15H14ClF2NO5
IUPAC name	(1R,2R,3R,5R,6R)-2-amino-3-[(4-chloro-3-fluorophenyl)methoxy]-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight	361.726
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	-1.2
Synonyms	BDBM50151449 (1R,2R,3R,5R,6R)-2-Amino-3-(4-chloro-3-fluoro-benzyloxy)-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Inchi Key	BBANVACNTZLDHJ-JAGWWQSPSA-N
Inchi ID	InChI=1S/C15H14ClF2NO5/c16-8-2-1-6(3-9(8)17)5-24-10-4-7-11(14(7,18)12(20)21)15(10,19)13(22)23/h1-3,7,10-11H,4-5,19H2,(H,20,21)(H,22,23)/t7-,10-,11+,14-,15+/m1/s1
PubChem CID	11360426
ChEMBL	CHEMBL362325
IUPHAR	N/A
BindingDB	50151449
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
19342	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
557861	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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