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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL395844
Molecular formula	C15H14ClFN4O
IUPAC name	2-[(E)-[2-[(4-chlorophenyl)methoxy]-3-fluorophenyl]methylideneamino]guanidine
Molecular weight	320.752
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.7
Synonyms	BDBM50197771 Hydrazinecarboximidamide, 2-[[3-fluoro-2-[(4-chlorophenyl)methoxy]phenyl]methylene]-, (2E)- (2E)-2-{2-[(4-chlorobenzyl)oxy]-3-fluorobenzylidene}hydrazinecarboximidamide 1-[(E)-[2-[(4-chlorophenyl)methoxy]-3-fluoro-phenyl]methyleneamino]guanidine
Inchi Key	AYUTVIVIEVCEQQ-DNTJNYDQSA-N
Inchi ID	InChI=1S/C15H14ClFN4O/c16-12-6-4-10(5-7-12)9-22-14-11(2-1-3-13(14)17)8-20-21-15(18)19/h1-8H,9H2,(H4,18,19,21)/b20-8+
PubChem CID	16728633
ChEMBL	CHEMBL395844
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17805	C-C chemokine receptor type 5	P51681	CCR5	Homo sapiens (Human)	352

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