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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL21278
Molecular formula	C22H34N4O
IUPAC name	N'-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl]-N'-methylhexane-1,6-diamine
Molecular weight	370.541
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.8
Synonyms	N-[2-[N-(4-methoxybenzyl)-N-(2-pyridyl)amino]ethyl]-N-methyl-1,6-hexanediamine AYEQNAFPDMJGOZ-UHFFFAOYSA-N SCHEMBL9574840 BDBM50404154 N-(4-Methoxybenzyl)-N-[2-[methyl(6-aminohexyl)amino]ethyl]pyridine-2-amine
Inchi Key	AYEQNAFPDMJGOZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H34N4O/c1-25(16-8-4-3-6-14-23)17-18-26(22-9-5-7-15-24-22)19-20-10-12-21(27-2)13-11-20/h5,7,9-13,15H,3-4,6,8,14,16-19,23H2,1-2H3
PubChem CID	19762600
ChEMBL	CHEMBL21278
IUPHAR	N/A
BindingDB	50404154
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17386	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
17387	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488

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