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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3691823
Molecular formula	C23H18F4N4O2
IUPAC name	(4-fluoro-2-pyrimidin-2-ylphenyl)-[6-[5-(trifluoromethyl)pyridin-2-yl]oxy-2-azabicyclo[2.2.1]heptan-2-yl]methanone
Molecular weight	458.417
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	3.9
Synonyms	US8969352, 20 US8969352, 26 BDBM143759 SCHEMBL16045600
Inchi Key	AXZNZGVQOXKZLA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H18F4N4O2/c24-15-3-4-16(17(10-15)21-28-6-1-7-29-21)22(32)31-12-13-8-18(31)19(9-13)33-20-5-2-14(11-30-20)23(25,26)27/h1-7,10-11,13,18-19H,8-9,12H2
PubChem CID	86271886
ChEMBL	CHEMBL3691823
IUPHAR	N/A
BindingDB	143759
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
465005	Orexin receptor type 1	P56718	Hcrtr1	Rattus norvegicus (Rat)	416
517411	Orexin receptor type 1	O43613	HCRTR1	Homo sapiens (Human)	425
465004	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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