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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL187366
Molecular formula	C19H17F3N8O
IUPAC name	2-(furan-2-yl)-5-[4-[(2,3,6-trifluorophenyl)methyl]piperazin-1-yl]-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
Molecular weight	430.395
Hydrogen bond acceptor	11
Hydrogen bond donor	1
XlogP	2.3
Synonyms	BDBM50151181 2-Furan-2-yl-5-[4-(2,3,6-trifluoro-benzyl)-piperazin-1-yl]-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-ylamine
Inchi Key	AXSTVTUNUISZFM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H17F3N8O/c20-12-3-4-13(21)15(22)11(12)10-28-5-7-29(8-6-28)18-25-17(23)30-19(26-18)24-16(27-30)14-2-1-9-31-14/h1-4,9H,5-8,10H2,(H2,23,24,25,26,27)
PubChem CID	11774744
ChEMBL	CHEMBL187366
IUPHAR	N/A
BindingDB	50151181
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17053	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
17054	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410

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