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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	methoxymethyl-MTEP
Molecular formula	C13H12N2OS
IUPAC name	4-[2-[5-(methoxymethyl)pyridin-3-yl]ethynyl]-2-methyl-1,3-thiazole
Molecular weight	244.312
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	2.0
Synonyms	DTXSID90438611 CHEMBL1169453 3-(methoxymethyl)-5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine D0S3BD [3H]-methoxymethyl-MTEP AWDRAHDWMICWJM-UHFFFAOYSA-N GTPL3345 3-(2-Methyl-4-thiazolylethynyl)-5-(methoxymethyl)pyridine CHEMBL420533 Pyridine, 3-(methoxymethyl)-5-[(2-methyl-4-thiazolyl)ethynyl]- 3-Methoxymethyl-5-(2-methyl-thiazol-4-ylethynyl)-pyridine 524924-75-2 D0S7SE [3H]methoxymethyl-MTEP BDBM50366853 GTPL5394 3-(methoxymethyl)-5-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine CTK1E4453 SCHEMBL5652003 [ Show all ]
Inchi Key	AWDRAHDWMICWJM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H12N2OS/c1-10-15-13(9-17-10)4-3-11-5-12(8-16-2)7-14-6-11/h5-7,9H,8H2,1-2H3
PubChem CID	10354477
ChEMBL	N/A
IUPHAR	5394, 3345
BindingDB	50366853
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15910	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
553327	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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