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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL561189
Molecular formula	C19H14ClNO
IUPAC name	(E)-3-(2-chloro-8-methylquinolin-3-yl)-1-phenylprop-2-en-1-one
Molecular weight	307.777
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	5.3
Synonyms	BAS 02276957 3-(2-Chloro-8-methyl-quinolin-3-yl)-1-phenyl-propenone AC1NY5KB BDBM50296667 (2E)-3-(2-chloro-8-methyl(3-quinolyl))-1-phenylprop-2-en-1-one ST50263492 3-(2-chloro-8-methylquinolin-3-yl)-1-phenylprop-2-en-1-one AKOS000638581 (E)-3-(2-chloro-8-methylquinolin-3-yl)-1-phenylprop-2-en-1-one ZINC4350125 [ Show all ]
Inchi Key	ATJXEFUUCNCHAP-ZHACJKMWSA-N
Inchi ID	InChI=1S/C19H14ClNO/c1-13-6-5-9-15-12-16(19(20)21-18(13)15)10-11-17(22)14-7-3-2-4-8-14/h2-12H,1H3/b11-10+
PubChem CID	5766225
ChEMBL	CHEMBL561189
IUPHAR	N/A
BindingDB	50296667
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
14017	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
14016	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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