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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	TAK-220
Molecular formula	C31H41ClN4O3
IUPAC name	1-acetyl-N-[3-[4-[(4-carbamoylphenyl)methyl]piperidin-1-yl]propyl]-N-(3-chloro-4-methylphenyl)piperidine-4-carboxamide
Molecular weight	553.144
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.2
Synonyms	1-acetyl-N-[3-[4-[(4-carbamoylphenyl)methyl]-1-piperidyl]propyl]-N-(3-chloro-4-methyl-phenyl)piperidine-4-carboxamide 928QIN0R16 D0O9UC TAK 220;TAK220 333994-00-6 AKOS027337128 HY-19974 TBR-220 ZINC6718478 1-acetyl-N-(3-(4-(4-carbamoylbenzyl)piperidin-1-yl)propyl)-N-(3-chloro-4-methylphenyl)piperidine-4-carboxamide 674782-27-5 CHEMBL207004 SCHEMBL3034679 1-acetyl-N-[3-[4-[(4-carbamoylphenyl)methyl]piperidin-1-yl]propyl]-N-(3-chloro-4-methylphenyl)piperidine-4-carboxamide AC1NQNHO DTXSID00187027 4-Piperidinecarboxamide, 1-acetyl-N-[3-[4-[[4-(aminocarbonyl)phenyl]methyl]-1-piperidinyl]propyl]-N-(3-chloro-4-methylphenyl)- BDBM50185979 L000798 TBR220 1-acetyl-N-(3-{4-((4-carbamoylphenyl)methyl)piperidin-1-yl}propyl)-N-(3-chloro-4-methylphenyl)piperidine-4-carboxamide CS-5579 TAK 220 1-acetyl-N-{3-[4-(4-carbamoylbenzyl)piperidin-1-yl]propyl}-N-(3-chloro-4-methylphenyl)piperidine-4-carboxamide AIDS228341 GTPL800 TAK220 SB16979 UNII-928QIN0R16 [ Show all ]
Inchi Key	ASSJTMUEFHUKMJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H41ClN4O3/c1-22-4-9-28(21-29(22)32)36(31(39)27-12-18-35(19-13-27)23(2)37)15-3-14-34-16-10-25(11-17-34)20-24-5-7-26(8-6-24)30(33)38/h4-9,21,25,27H,3,10-20H2,1-2H3,(H2,33,38)
PubChem CID	5275766
ChEMBL	CHEMBL207004
IUPHAR	800
BindingDB	50185979
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
13479	C-C chemokine receptor type 5	P51681	CCR5	Homo sapiens (Human)	352

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