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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1258403
Molecular formula	C21H19ClN4O3S
IUPAC name	1-[(6S)-6-(5-chloro-2-methoxyphenyl)-3-methylsulfanyl-6H-[1,2,4]triazino[5,6-d][3,1]benzoxazepin-7-yl]propan-1-one
Molecular weight	442.918
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.8
Synonyms	AC1O49OG 1-[(6S)-6-(5-chloro-2-methoxyphenyl)-3-methylsulfanyl-6H-[1,2,4]triazino[5,6-d][3,1]benzoxazepin-7-yl]propan-1-one BDBM50416892 ZINC684535
Inchi Key	ARAZRORIKVPFFZ-FQEVSTJZSA-N
Inchi ID	InChI=1S/C21H19ClN4O3S/c1-4-17(27)26-15-8-6-5-7-13(15)18-19(23-21(30-3)25-24-18)29-20(26)14-11-12(22)9-10-16(14)28-2/h5-11,20H,4H2,1-3H3/t20-/m0/s1
PubChem CID	6402208
ChEMBL	CHEMBL1258403
IUPHAR	N/A
BindingDB	50416892
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12268	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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