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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL191874
Molecular formula	C28H35NO5
IUPAC name	7-[(2R)-2-[3-[3-(4-hydroxy-2-methylphenyl)phenyl]-3-oxopropyl]-6-oxopiperidin-1-yl]heptanoic acid
Molecular weight	465.59
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.6
Synonyms	BDBM50166474 SCHEMBL14261762 7-{(R)-2-[3-(4''-Hydroxy-2''-methyl-biphenyl-3-yl)-3-oxo-propyl]-6-oxo-piperidin-1-yl}-heptanoic acid
Inchi Key	AOXJIHSGSFPGMK-HSZRJFAPSA-N
Inchi ID	InChI=1S/C28H35NO5/c1-20-18-24(30)14-15-25(20)21-8-6-9-22(19-21)26(31)16-13-23-10-7-11-27(32)29(23)17-5-3-2-4-12-28(33)34/h6,8-9,14-15,18-19,23,30H,2-5,7,10-13,16-17H2,1H3,(H,33,34)/t23-/m1/s1
PubChem CID	24771583
ChEMBL	CHEMBL191874
IUPHAR	N/A
BindingDB	50166474
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10673	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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