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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	353231-17-1
Molecular formula	C21H19F3N2O4S
IUPAC name	2,2,2-trifluoro-N-[4-(2-methoxyphenoxy)phenyl]-N-(pyridin-3-ylmethyl)ethanesulfonamide
Molecular weight	452.448
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	4.1
Synonyms	ALMACYDZFBMGOR-UHFFFAOYSA-N FT-0715485 N-(4-(2-methoxyphenoxy)phenyl)-N-(2,2,2-trifluoroethylsulfonyl)pyrid-3-ylmethylamine 2,2,2-trifluoro-N-[4-(2-methoxyphenoxy)phenyl]-N-(pyridin-3-ylmethyl)ethanesulfonamide 4-MPPTS BDBM50130608 LS-191567 ZINC1494188 AJ-26351 D08BXD LY487379 2,2,2-TRIFLUORO-N-(4-(2-METHOXYPHENOXY)PHENYL)-N-(PYRIDIN-3-YLMETHYL)ETHANESULFONAMIDE API0007634 GTPL1402 NCGC00378807-01 2,2,2-tris(fluoranyl)-N-[4-(2-methoxyphenoxy)phenyl]-N-(pyridin-3-ylmethyl)ethanesulfonamide LY-487,379 AKOS016013857 DTXSID10431366 N-(4-(2-Methoxyphenoxy)phenyl)-N-(2,2,2-trifluoroethanesulfonyl)pyrid-3-ylmethylamine 2,2,2-trifluoro-N-[4-(2-methoxyphenoxy)phenyl]-N-(3-pyridinylmethyl)ethanesulfonamide AX8249515 KB-224796 SCHEMBL3805847 A822730 CHEMBL108939 LY-487379 2,2,2-Trifluoro-ethanesulfonic acid [4-(2-methoxy-phenoxy)-phenyl]-pyridin-3-ylmethyl-amide [ Show all ]
Inchi Key	ALMACYDZFBMGOR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H19F3N2O4S/c1-29-19-6-2-3-7-20(19)30-18-10-8-17(9-11-18)26(14-16-5-4-12-25-13-16)31(27,28)15-21(22,23)24/h2-13H,14-15H2,1H3
PubChem CID	9825084
ChEMBL	CHEMBL108939
IUPHAR	1402
BindingDB	50130608
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8380	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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