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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL236035
Molecular formula	C23H15IN2O
IUPAC name	4-(3-iodophenyl)-8-(2-phenylethynyl)-1,3-dihydro-1,5-benzodiazepin-2-one
Molecular weight	462.29
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.1
Synonyms	(E)-4-(3-iodophenyl)-8-(2-phenylethynyl)-1H-benzo[b][1,4]diazepin-2(3H)-one AIYLGSKMEDZTFH-UHFFFAOYSA-N 4-(3-Iodo-phenyl)-8-phenylethynyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one BDBM50225802 SCHEMBL5868764
Inchi Key	AIYLGSKMEDZTFH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H15IN2O/c24-19-8-4-7-18(14-19)21-15-23(27)26-22-13-17(11-12-20(22)25-21)10-9-16-5-2-1-3-6-16/h1-8,11-14H,15H2,(H,26,27)
PubChem CID	22224695
ChEMBL	CHEMBL236035
IUPHAR	N/A
BindingDB	50225802
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6650	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
557474	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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