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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL327478
Molecular formula	C29H33ClN2
IUPAC name	1-[[(3S,4S)-1-benzyl-4-(2-chlorophenyl)pyrrolidin-3-yl]methyl]-4-phenylpiperidine
Molecular weight	445.047
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	6.4
Synonyms	1-[[(3S,4S)-1-benzyl-4-(2-chlorophenyl)pyrrolidin-3-yl]methyl]-4-phenyl-piperidine CTK6H3117 (+/-)-rel-Piperidine, 1-[[(3S,4S)-4-(2-chlorophenyl)-1-(phenylmethyl)-3-pyrrolidinyl]methyl]-4-phenyl- 1-[[(3S,4S)-1-benzyl-4-(2-chlorophenyl)pyrrolidin-3-yl]methyl]-4-phenylpiperidine AC1LAKAZ 1-[(3S,4S)-1-Benzyl-4-(2-chloro-phenyl)-pyrrolidin-3-ylmethyl]-4-phenyl-piperidine 1-{[(3s,4s)-1-benzyl-4-(2-chlorophenyl)pyrrolidin-3-yl]methyl}-4-phenylpiperidine BDBM50105530 [ Show all ]
Inchi Key	AIBUJZOURZLWNC-XCZPVHLTSA-N
Inchi ID	InChI=1S/C29H33ClN2/c30-29-14-8-7-13-27(29)28-22-32(19-23-9-3-1-4-10-23)21-26(28)20-31-17-15-25(16-18-31)24-11-5-2-6-12-24/h1-14,25-26,28H,15-22H2/t26-,28-/m0/s1
PubChem CID	489828
ChEMBL	CHEMBL327478
IUPHAR	N/A
BindingDB	50105530
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6092	C-C chemokine receptor type 5	P51681	CCR5	Homo sapiens (Human)	352

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