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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	FR-166124
Molecular formula	C25H22N4O3
IUPAC name	2-[2-[6-oxo-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)pyridazin-1-yl]cyclohexen-1-yl]acetic acid
Molecular weight	426.476
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.9
Synonyms	L013227 3-[2-(2-carboxymethyl-1-cyclohexenyl)-3-oxo-2,3-dihydropyridazin-6-yl]-2-phenylpyrazolo[1,5-a]pyridine BDBM50079650 D0F9JF SCHEMBL6050347 {2-[6-Oxo-3-(2-phenyl-pyrazolo[1,5-a]pyridin-3-yl)-6H-pyridazin-1-yl]-cyclohex-1-enyl}-acetic acid AHLONZJYCGNSFG-UHFFFAOYSA-N CHEMBL59673 [ Show all ]
Inchi Key	AHLONZJYCGNSFG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H22N4O3/c30-22-14-13-19(26-29(22)20-11-5-4-10-18(20)16-23(31)32)24-21-12-6-7-15-28(21)27-25(24)17-8-2-1-3-9-17/h1-3,6-9,12-15H,4-5,10-11,16H2,(H,31,32)
PubChem CID	9910335
ChEMBL	CHEMBL59673
IUPHAR	N/A
BindingDB	50079650
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5658	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
5657	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410

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