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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2315925
Molecular formula	C24H27F3N6O2S
IUPAC name	N-[1-[4-hydroxy-4-(2-methyl-1,3-thiazol-5-yl)cyclohexyl]azetidin-3-yl]-2-[[6-(trifluoromethyl)quinazolin-4-yl]amino]acetamide
Molecular weight	520.575
Hydrogen bond acceptor	11
Hydrogen bond donor	3
XlogP	3.4
Synonyms	SCHEMBL9999076 BDBM50425702 CHEMBL3704095 US9062048, 79 AFSXROFWADTOSY-UHFFFAOYSA-N N-(1-(4-hydroxy-4-(2-methylthiazol-5-yl)cyclohexyl)azetidin-3-yl)-2-((6-(trifluoromethyl)quinazolin-4-yl)amino)acetamide BDBM163451 [ Show all ]
Inchi Key	AFSXROFWADTOSY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H27F3N6O2S/c1-14-28-9-20(36-14)23(35)6-4-17(5-7-23)33-11-16(12-33)32-21(34)10-29-22-18-8-15(24(25,26)27)2-3-19(18)30-13-31-22/h2-3,8-9,13,16-17,35H,4-7,10-12H2,1H3,(H,32,34)(H,29,30,31)
PubChem CID	68004012
ChEMBL	CHEMBL3704095
IUPHAR	N/A
BindingDB	163451
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
459261	C-C chemokine receptor-like 2	O00421	CCRL2	Homo sapiens (Human)	344

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