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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1629856
Molecular formula	C25H22F3N3O
IUPAC name	4-[3-(2-ethyl-6-methylpyridin-4-yl)phenyl]-7-methyl-8-(trifluoromethyl)-1,3-dihydro-1,5-benzodiazepin-2-one
Molecular weight	437.466
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.5
Synonyms	BDBM50332964 SCHEMBL5557475 4-(3-(2-ethyl-6-methylpyridin-4-yl)phenyl)-7-methyl-8-(trifluoromethyl)-1H-benzo[b][1,4]diazepin-2(3H)-one AFSJGBXRHLXBHV-UHFFFAOYSA-N 4-[3-(2-Ethyl-6-methyl-pyridin-4-yl)-phenyl]-7-methyl-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one
Inchi Key	AFSJGBXRHLXBHV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H22F3N3O/c1-4-19-11-18(9-15(3)29-19)16-6-5-7-17(10-16)21-13-24(32)31-23-12-20(25(26,27)28)14(2)8-22(23)30-21/h5-12H,4,13H2,1-3H3,(H,31,32)
PubChem CID	11351088
ChEMBL	CHEMBL1629856
IUPHAR	N/A
BindingDB	50332964
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4431	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
557408	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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