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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL377969
Molecular formula	C18H17BrN4O2
IUPAC name	1-(4-bromophenyl)-3-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)urea
Molecular weight	401.264
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	2.1
Synonyms	MolPort-003-815-885 BDBM50186943 SR-01000094397 1-(4-bromophenyl)-3-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)urea AC1LOHBE N-(4-bromophenyl)-N'-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea CCG-128225 SR-01000094397-1 1-(4-bromophenyl)-3-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)urea MCULE-6431150636 AKOS001801810 Oprea1_323848 ZINC1028240 [ Show all ]
Inchi Key	AFNFUDZGKRZEER-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H17BrN4O2/c1-12-16(21-18(25)20-14-10-8-13(19)9-11-14)17(24)23(22(12)2)15-6-4-3-5-7-15/h3-11H,1-2H3,(H2,20,21,25)
PubChem CID	1240119
ChEMBL	CHEMBL377969
IUPHAR	N/A
BindingDB	50186943
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4287	N-formyl peptide receptor 2	P25090	FPR2	Homo sapiens (Human)	351

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