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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1LXTED
Molecular formula	C19H11NO4S2
IUPAC name	(5Z)-5-[(6-hydroxy-4-oxochromen-3-yl)methylidene]-3-phenyl-2-sulfanylidene-1,3-thiazolidin-4-one
Molecular weight	381.42
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.8
Synonyms	(5Z)-5-[(6-hydroxy-4-oxo-4H-chromen-3-yl)methylidene]-3-phenyl-2-thioxo-1,3-thiazolidin-4-one ZINC2226048 5-[1-(6-Hydroxy-4-oxo-4H-chromen-3-yl)-meth-(Z)-ylidene]-3-phenyl-2-thioxo-thiazolidin-4-one HMS2768C19 AKOS005498946 SMR000221488 (5Z)-5-[(6-hydroxy-4-oxochromen-3-yl)methylidene]-3-phenyl-2-sulfanylidene-1,3-thiazolidin-4-one CHEMBL1610416 896836-74-1 MLS000332025 (5Z)-5-[(6-hydroxy-4-keto-chromen-3-yl)methylene]-3-phenyl-2-thioxo-thiazolidin-4-one BDBM84390 STK574230 (Z)-5-((6-hydroxy-4-oxo-4H-chromen-3-yl)methylene)-3-phenyl-2-thioxothiazolidin-4-one cid_1857878 MolPort-002-640-983 [ Show all ]
Inchi Key	ADTOQDFJFAQTAP-PXNMLYILSA-N
Inchi ID	InChI=1S/C19H11NO4S2/c21-13-6-7-15-14(9-13)17(22)11(10-24-15)8-16-18(23)20(19(25)26-16)12-4-2-1-3-5-12/h1-10,21H/b16-8-
PubChem CID	1857878
ChEMBL	CHEMBL1610416
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3075	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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