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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL284010
Molecular formula	C32H40F2N2O4
IUPAC name	4-[1-[[(3S,4S)-1-[(1R)-1-carboxy-2-cyclopropylethyl]-4-(3-fluorophenyl)pyrrolidin-3-yl]methyl]piperidin-4-yl]-2-(4-fluorophenyl)butanoic acid
Molecular weight	554.679
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	1.7
Synonyms	BDBM50121839 4-{1-[(S)-1-(1-Carboxy-2-cyclopropyl-ethyl)-4-((R)-3-fluoro-phenyl)-pyrrolidin-3-ylmethyl]-piperidin-4-yl}-2-(4-fluoro-phenyl)-butyric acid
Inchi Key	ADFRLQLNMJKEBV-XNUHKXAHSA-N
Inchi ID	InChI=1S/C32H40F2N2O4/c33-26-9-7-23(8-10-26)28(31(37)38)11-6-21-12-14-35(15-13-21)18-25-19-36(30(32(39)40)16-22-4-5-22)20-29(25)24-2-1-3-27(34)17-24/h1-3,7-10,17,21-22,25,28-30H,4-6,11-16,18-20H2,(H,37,38)(H,39,40)/t25-,28?,29+,30+/m0/s1
PubChem CID	44273850
ChEMBL	CHEMBL284010
IUPHAR	N/A
BindingDB	50121839
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2235	C-C chemokine receptor type 5	P51681	CCR5	Homo sapiens (Human)	352

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